Can Stem Cells Cure Obesity?

In this study, researchers have used artificial proteins (peptides) to identify a specific marker on the surface of adipose stem cells.

“This marker, called delta-decorin, is specifically expressed on the surface of adipose stem cells, which are responsible for the production of white adipose tissue,” said Mikhail Kolonin, Ph.D., the study’s senior author. “This is the first prospective marker to be discovered for this particular type of adult stem cell.”

Alexes Daquinag, Ph.D., the study’s first author, said “In obesity, you have an overgrowth of white adipose tissue. It is made of adipocytes (fat cells) and one way to stop obesity is to target the progenitor cells — adipose stem cells.”

Adipose stem cells Can Stem Cells Cure Obesity?

Adipose Stem Cells

The researchers also noted that delta-decorin interacts with another protein called resistin on the surface of adipose stem cells.

“The decorin-resistin connection is particularly interesting because both decorin and resistin have been previously implicated in Type-2 diabetes and other inflammation-related disease,” Kolonin said.

So, not only are they looking at a treatment for obesity…they’re looking at treating all of the nasty inflammation related diseases plaguing our society

“The next step will involve preclinical tests to see if we can develop the identified peptide into compounds that target these adipose stem cells,” Kolonin said. “By depleting the adipose tissue progenitors, we may be able to provide long-term control of white fat.”

Conclusion

As a big health & fitness geek, this kind of research makes me giddy like a little school-girl.

However….we have to remember that this research is highly experimental and even if they do eventually find an effective stem cell treatment for obesity et al, that treatment is probably decades away.

Until then, you’ve got diet & exercise.

 

Doug Robb is a personal trainer, a fitness blogger and author, a competitive athlete, a social media nerd and a student of nutrition and exercise science. Since 2008, Doug has brought his real-world experience online via his health & fitness blog, Health Habits.

2 Comments

  1. stem cell discussion

    September 18, 2011 at 10:16 am

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  2. Vicki Kron

    June 18, 2011 at 6:08 am

    Diet and exercise vs. Stem Cell management of adipose tissue. Which would I choose? Letting someone else manage our fat would probably be everyone’s choice.

    But it wouldn’t solve the problem of the food products being manufactured in our country that are detrimental to human beings and animals too. How can we reverse the trend of producing food that is making these companies tons of money, but is making the rest of us fat and unhealthy?

    My hope is that scientists will work on this!

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