Here we go again.
Researchers at Sirtis (owned by Glaxo-SmithKline) are testing a new diet drug that would allow the couch potatoes of the world to eat whatever they want and never gain an ounce.
Wait, it gets better.
It would also rid the planet of Type 2 Diabetes.
It gets even better.
They are developing other versions that promise to extend the average life span while preventing heart disease, cancer and Alzheimer’s disease.
Wow!
This sounds great…Tell me more.
OK
This particular drug, SRT1720, fools the body into thinking food is scarce and it has to burn off fat to survive.
It does this by triggering a protein called SIRT1 that plays a key role in regulating the body’s supply of energy.
So how did they come up with the idea for this wonder drug?
Researchers discovered the importance of the SIRT1 protein by studying the metabolic effects shown by the natural supplement, Resveratrol.
But where Resveratrol affects many other systems in the body, SRT1720 targets “only the SIRT1 pathway, making it more selective and potent for achieving these metabolic benefits”.
Oh, and because it is a synthetic substance, designed by a pharmaceutical company, it can be patented.
And make billions and billions of dollars.
I wonder how the GSK execs reacted to that bit of good news.
But wait, let’s be fair here. It’s not like they could just produce a high dose Resveratrol supplement at 1/4 the price while still maintaining all of the heart healthy, anti-cancer, anti-Alzheimer’s effects.
Oh, wait a second.
Oh well, that’s the HEALTH CARE business.
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I was interested in the part where you said, “This particular drug, SRT1720, fools the body into thinking food is scarce and it has to burn off fat to survive”.
My understanding is that when the body thinks that the food scarce, it does its best to store it. Thats why diets become less effective with time as the body thinks food is scarce!
Pharmaceuticals have done much good in fighting disease, but I will not be one of the first (more like the last) to prescribe another miracle diet pill with who knows what long-term side effects.
This trial was done only on mice. So, do you think you should have shown a mouse with the capsule on its painted lips?
I’ll believe it when I see it. Plus, everytime a new drug comes out, there is a list of side effects a mile long.
Thanks, but no thanks………..:)
I am with Lisa Newton!
Rambodoc…I tried, but the damn mouse wouldn’t sit still
Charlie,
You’re right that when food is scarce, our metabolism / energy expenditure drops off.
But along with that effect, the body does have to shift to body-fat stores and muscle mass to make up the difference in available energy.
I am curious to see how this drug does in future tests.
It’s funny how often new drugs come down the pipeline claiming to have discovered some master hormone/enzyme/etc.. that will give us a quick and easy answer to obesity.
I don’t think that they will ever identify a single cause for obesity.
Every bite of food we take involves hundreds of different chemical compounds and hormones and enzymes….
Never mind the effects of stress, pollution, antibiotics and steroids in our meat, pesticides, herbicides, GMOs, lack of physical activity, etc…
I don’t know if this would be a good thing or not, but I have to admit I’d try it.